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Also on the Essential Path · 11/18

Transhumanism: From Healing to Transforming the Human Being

From gene therapy and prostheses that treat disease or restore lost function to BCIs, heritable modification and the posthuman ideal: where does medicine stop serving the person and begin adapting the person to a technological system?

If a pacemaker preserves a life, a prosthesis restores a lost grasp, or gene therapy treats a severe inherited disease, technology is serving the healing of a person. That is not the same thing as deliberately upgrading a healthy person, implanting new technical capacities, or progressively linking them to machine systems because the natural human body is presumed to be insufficient.

This article therefore does not treat transhumanism as an inevitable next stage of development but as an idea that deserves critical scrutiny. Medicine already uses gene therapy, neurostimulation, implants, and advanced prostheses for treatment and restoration. The more radical goal — exceeding ordinary human capacities, redesigning the healthy body, or moving toward a posthuman condition — is a different ethical project, not merely medicine continued.

The human being is not an obsolete platform in need of an upgrade. Treatment that restores health or lost function can be ethically defended. Technological redesign of a healthy person carries a far heavier evidential and moral burden — especially when it creates lasting dependence of the body, nervous system, or identity on devices, software, companies, or institutions.

What does transhumanism actually mean?

Contemporary transhumanism is best understood as a family of views, not a single organization, party, or unified plan. Its common idea is that current human biology need not be the final boundary and that some limitations might be reduced or exceeded through biomedicine, information technology, neurotechnology, genetics, or other technical means. Transhumanists differ widely, but the shared premise matters: the human being becomes something that may be deliberately technologically redesigned.

That does not mean every laboratory, company, or influential individual belongs to one hidden transhumanist plan. Such a claim must be demonstrated, not assumed. But when organizations and powerful technology actors openly advocate expanded capacities, radical life extension, brain-device integration, or other forms of enhancement, it is entirely legitimate to scrutinize their stated aims critically. This article therefore rejects both an unsupported theory of one all-controlling center and the opposite naivety that treats publicly declared transhumanist ambitions as value-neutral technological fashion.

The word has a longer intellectual prehistory, but biologist Julian Huxley in 1957 gave the term an influential modern programmatic meaning: humans might use knowledge to consciously move beyond some present limitations. During the 1980s and 1990s, contemporary transhumanism developed around futurist and technology-oriented circles, including the Extropy Institute, later the World Transhumanist Association, and other networks. The Transhumanist Declaration was first formulated in 1998 and revised in subsequent years.

This history is not a straight causal line to modern medicine. The desire for longer life and better health predates the word transhumanism, while medicine has its own aims. Yet the intellectual genealogy still matters because it reveals a shift from healing the human being toward the idea that the human being as a biological creature may be deliberately surpassed. The separate history of eugenics and coercive projects of 'population improvement' will therefore be handled in Eugenics: How “Improving Humanity” Became a Political Project, where actual links can be established precisely without guilt by association or historical shortcuts.

The classic distinction separates therapy, which prevents disease or restores lost function, from enhancement, which seeks to raise a healthy capacity beyond an ordinary level or add a capacity the human body does not naturally possess. The boundary is not mathematically sharp in every case, but that does not make it morally irrelevant. Purpose, risk, reversibility, effects on descendants, and the ability to refuse create very different ethical situations.

For THY-REALITY, the basic value boundary is clear: treating disease, reducing suffering, and restoring lost function are fundamentally different from technologically redesigning a healthy person. With enhancement, the burden of proof is not merely whether something technically works. We must also ask why it is good for a person to replace or supplement natural capacities with invasive technology, who will control that system, and what happens to people who refuse the 'upgrade.'

Glasses, vaccines, and prostheses are not an argument for cyborgization

Humans have used tools, writing, education, glasses, medicines, and machines for millennia. But it does not follow that technological merging of human and machine is simply another unproblematic step in the same process. Glasses correct an optical system; a vaccine prevents disease; a prosthesis can restore function after amputation. A technological aid is not, by itself, a transhumanist upgrade.

A high-quality bionic prosthesis that restores grasp can be an extraordinary medical achievement. A different category is a device intended to give a healthy body supernormal capacities or bind it to permanent technical infrastructure. Research on direct neural interfaces, sensory feedback, and osseointegration is valuable for rehabilitation; that is precisely why it should not be used as a rhetorical bridge to the claim that upgrading healthy humans is merely the natural continuation of treatment.

Genetic technology shows why present fact must be separated from future vision. In December 2023, the U.S. FDA approved Casgevy, the first approved treatment using a CRISPR/Cas9-type genome-editing technology, for some patients with sickle cell disease; later approvals expanded its use. This is an important medical achievement, but its purpose is not the production of a 'better human' — its purpose is the treatment of serious disease.

Casgevy also illustrates the distinction between somatic editing and heritable change. A patient's own blood-forming stem cells are edited, and the change is not intended to pass to future generations. When discussion moves to germ cells, embryos, and heritable modification, the ethical situation changes: we are no longer dealing only with treatment of a person who can consent, but potentially with the biological inheritance of people who never had a choice.

WHO distinguishes somatic, germline, and heritable human genome editing and emphasizes robust governance. Its public position continues to warn that it would be irresponsible to proceed to clinical applications of heritable germline genome editing before scientific, safety, and governance conditions are met. With interventions that may pass to future generations, uncertainty is therefore not a side issue but a central problem.

Bioethical debate is not completely uniform, and some documents leave open a possible future pathway under very strict conditions. This article nevertheless takes a clearer value position: heritable design of healthy children for preferred traits is not medical treatment, and we do not treat it as an acceptable path of human development. Technical possibility does not create a moral right for one generation to engineer the next according to current cultural, market, or aesthetic preferences.

An illustration of the CRISPR-Cas9 system showing targeted genome editing of DNA.
A CRISPR-Cas9 illustration from the National Human Genome Research Institute. This article uses it as an example of **therapeutic** genetic technology: treating disease is not the same as heritable or enhancement-oriented redesign of healthy humans. Image: Ernesto del Aguila III / National Human Genome Research Institute, NIH / Wikimedia Commons Public domain — U.S. federal government / NIH work

Brains and machines: assistance is one thing, merging is another

Brain-computer interfaces are often presented as a direct bridge to a transhumanist future. Their strongest clinical motivation today is far more concrete: restoring some lost autonomy to people with paralysis, amputation, or severe communication impairment. In that setting, technology serves the person where disease or injury has taken function away.

Implanting or permanently linking healthy brains to machines for greater cognitive capacity, continuous digital access, or competitive advantage is a different question entirely. Current evidence does not show that such redesign of healthy humans is safe, necessary, or wise. This article therefore does not accept the phrase 'human-machine merger' as neutral progress: where an intervention is not treatment, we must ask what a person gains, what they hand over to the system, and what they become dependent on.

When technology directly measures or modulates the nervous system, the issue is no longer purely medical. In November 2025, UNESCO adopted the first global recommendation on the ethics of neurotechnology, addressing dignity, mental privacy, autonomy, identity, and uses beyond medicine. The very need for such a framework illustrates that access to neural information is not comparable to an ordinary data point about a purchase or a location.

A device that helps a patient communicate is one thing; infrastructure that allows an employer, platform, military organization, or vendor to measure cognitive state, collect neural data, or remotely control implant functionality is another. The human interior must not become a new data colony. Mental privacy and the right not to enhance are therefore not side constraints on innovation but protections of personal sovereignty.

Extending healthy life is a legitimate medical goal. Geroscience seriously investigates biological mechanisms of aging and whether understanding them may reduce the burden of multiple age-related diseases. But treating disease and preserving health is not the same thing as the transhumanist promise of defeating death or achieving radical technological immortality.

Preclinical evidence also requires caution: methodological appraisals point to weaknesses in randomization, blinding, reporting, and translation between species. This article therefore does not oppose research into healthy aging; it opposes turning human fear of death into a market for grand technological promises that outrun evidence. Longer healthy life is a medical aim. The claim that mortality means the human being must become a technological project is a philosophical proposition that need not be accepted.

The LUKE Arm advanced bionic prosthesis from DARPA's Revolutionizing Prosthetics program.
The LUKE Arm from DARPA’s Revolutionizing Prosthetics program. It is shown as a medical example of restoring lost function — not as an argument that technological enhancement of healthy people is an obvious continuation of rehabilitation. Image: DARPA / Wikimedia Commons Public domain — U.S. federal government / DARPA work

Cognitive enhancement: more capacity is not more wisdom

Transhumanist writing often proposes better memory, attention, learning, mood, or decision-making. Yet 'cognition' is not one number that can simply be turned upward. Increased alertness can impair sleep; narrow focus may reduce breadth of attention; altered mood can change judgment. The human mind is a system of relationships and balances, not a processor with one performance slider.

The idea of technological 'moral' or personality enhancement is even more problematic. Who decides which emotions, traits, or styles of thought are optimal? This article gives priority to developing human capacities through learning, discipline, attention, creativity, bodily care, relationships, and conscious work on oneself rather than treating healthy brains as hardware requiring modification. More data-processing or neural capacity is not the same thing as greater wisdom, maturity, or freedom.

A traditional medical device is often imagined as an object that a clinician implants and that then serves the patient. Modern connected implants and neurotechnologies can instead depend on software, batteries, external controllers, algorithms, data formats, servicing, and the company that maintains the infrastructure. With a therapeutic device, that risk can sometimes be a reasonable price for restored function. With enhancement of a healthy person, deliberately creating a new permanent dependency is far harder to justify.

This is where transhumanism meets digital sovereignty. If a body or mind functions as intended only while a server, license, update channel, or proprietary protocol remains available, the user has not simply become 'more capable' — they have also become more bound to a technical system and its owners. Borgification: When the Human Becomes Part of the Network will examine ownership of body technology in detail; this article establishes the principle here: progress that reduces sovereignty over one's own body is not self-evidently progress.

Voluntariness: choice under pressure is not the same choice

A common transhumanist argument for freedom rests on bodily autonomy: adults should have broad authority over their own bodies. But a technological 'choice' changes when it affects employment, insurance, military fitness, education, or competitiveness. If an upgrade becomes a condition for keeping one's place, the decision is no longer fully free.

Bodily autonomy must therefore include a strong right not to enhance. A person who refuses an implant, neural monitoring, genetic modification, or another intervention must not become a second-class citizen, worker, or student. This article is deliberately resistant on this point: a technological standard must not become a new form of coercion merely because it is packaged as innovation, efficiency, or progress.

When a new technology is extremely expensive, its first social boundary is access. With treatment, unequal access is already a health problem; with enhancement it can also become a competitive and political problem. If wealthier people could purchase technical cognitive or physical advantages, markets could turn a voluntary enhancement into an expected standard.

There is no evidence that a caste of technologically 'upgraded' humans must necessarily emerge, and this article does not present that as certain. The concern is nonetheless serious enough to appear in bioethical and international frameworks. The critical point is different: when technology creates advantage only because others are forced to follow, the result is an upgrade race, not genuine freedom. Treatment aims at reducing suffering and enabling participation; competitive enhancement can make pressure itself part of the system.

Disability: treatment and assistance without an ideology of the 'corrected human'

Enhancement discourse can imply that every departure from statistical normality is a defect that should be corrected. This is especially sensitive in disability. An advanced prosthesis, cochlear implant, or neurotechnology may greatly increase one person's independence and quality of life; another person with the same diagnosis may also experience bodily or sensory difference as part of identity and community.

Criticism of transhumanist enhancement must therefore never become criticism of people who use medical devices. Restoring function and reducing suffering is not the same thing as an ideology that says humans should be technologically optimized. Genuine choice means access to treatment and assistive technology for those who want it, accessible environments for those who do not, and rejection of any standard under which a person's worth depends on proximity to a technically defined model of 'perfection.'

Any substantial change to body or brain can raise questions of identity. In therapy, the answer can be concrete: technology may restore communication, movement, or independence and thereby strengthen a person's authorship of their own life. Direct modification of a healthy brain for enhancement raises a different issue because the intervention is not restoring lost function but altering the organization of capacities, mood, or behavior itself.

It is therefore not enough to ask whether the user still feels like 'me.' We must also ask who sets the parameters of the change, who can access the data, who can update or disable the system, and whether the intervention can truly be abandoned. Technology can restore autonomy in illness; in enhancement it can also create new channels of external control or dependence beneath the appearance of greater capacity.

Descendants: when the choice is no longer only mine

With most somatic therapies, risk is borne mainly by the person choosing the intervention. Heritable genome editing changes the moral geometry. A modification may pass to descendants who did not choose it, while adverse effects might emerge only later. International frameworks therefore demand particular caution for interventions affecting future generations.

A transhumanist advocate may answer that non-intervention also affects future children. But in the case of enhancing healthy descendants, that does not remove the central issue: the preferences of one generation can become biologically preselected traits of the next. This article therefore supports a clear brake. Treating a severe inherited disease is one question; designing children for intelligence, appearance, performance, or other preferred traits crosses from medicine into human engineering, and we do not support that path.

In transhumanist literature, posthuman often refers to a hypothetical future condition in which human capacities have changed so profoundly that it becomes questionable whether the result remains human in today's biological or psychological sense. It may include radical longevity, greatly increased cognition, close integration with computers, or other changes. This is a philosophical and cultural goal in some currents, not an observed population or a scientifically determined next stage of evolution.

This article therefore does not present the posthuman ideal as a horizon humanity merely needs to engineer its way toward. Why should ceasing to be human count as a measure of human progress? Current evidence shows remarkable therapeutic achievements, difficult clinical limits, and many futuristic promises. Nothing requires us to derive an ideology of replacing the human being from the success of medicine. Human development can mean deeper development of consciousness, knowledge, character, relationships, and our own natural capacities — not necessarily putting ever more machinery inside the body.

Nine questions for every future 'upgrade'

For any technology that promises to enhance a healthy person, this article proposes a stricter review. 1. Is this treatment or enhancement of a healthy person? 2. Can the same goal be achieved through non-invasive development of the person's own capacities? 3. How strong is the evidence of benefit? 4. What are the risks and is the intervention genuinely reversible? 5. Who gains access to bodily or neural data? 6. Which vendor, software, or infrastructure does the person become dependent on? 7. Can the individual say no without penalty? 8. Does the effect extend to descendants? 9. Does the technology increase inequality or reduce human dignity and sovereignty?

These questions are deliberately not technophobic. Gene therapy for severe disease, a prosthesis after amputation, an experimental memory implant in a healthy adult, employer monitoring of brain activity, and heritable embryo design are not morally equivalent cases. The word innovation must not erase the differences between treatment, assistance, surveillance, and redesign of the human being.

Transhumanism raises an important question, but this article rejects a premise often hidden inside its most radical forms: that the human being is primarily an imperfect biological machine that progress should gradually repair, connect, and replace with better components. Medicine is valuable precisely because it heals the person. When technology moves from treatment to the demand that a healthy person become different, more connected, more optimized, and more dependent on artificial infrastructure, the relationship reverses: the person begins to serve an idea of technological progress.

THY-REALITY begins from a different philosophical position: it is not intellectually fair to equate the limits of human potential with the abilities we can currently measure in bodies and brains. We do not need to prove that human potential is literally mathematically infinite in order to reject the claim that our next step must be an implant, genetic enhancement, or merger with a machine. Treatment that restores health and freedom is worth supporting. For a healthy person, the stronger starting point is to cultivate what nature has already made possible — body, mind, consciousness, creativity, discipline, and relationships — while keeping technology in the role of tool, not master and not a new definition of the human being.

Sources and further reading

  1. Bostrom, Nick. A History of Transhumanist Thought. Journal of Evolution and Technology 14(1), 2005; Oxford University Research Archive — historical overview of modern transhumanist ideas and antecedents.
  2. Humanity+. The Transhumanist Declaration — primary self-description of one influential contemporary transhumanist organization; originally drafted in 1998 and later revised.
  3. Stanford Encyclopedia of Philosophy. Human Enhancement, substantive revision 13 November 2025 — conceptual and ethical overview of treatment/enhancement, justice, dignity, autonomy, and transhumanist/bioconservative debates.
  4. Racine, Eric et al. Is human enhancement also a personal matter? BMC Medical Ethics / PubMed — review of competing definitions of human enhancement and limits of a single consensual definition.
  5. U.S. Food and Drug Administration. FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease, 8 December 2023 — Casgevy as the first FDA-approved treatment using a novel genome-editing technology.
  6. U.S. Food and Drug Administration. FDA Approves First Gene Therapy for Young Children with Sickle Cell Disease, 1 July 2026 — supplemental Casgevy approval for patients aged two years and older with specified indications.
  7. World Health Organization. Human genome editing — current WHO overview distinguishing somatic, germline and heritable editing and reiterating governance concerns and the policy position on premature clinical heritable editing.
  8. World Health Organization. Human genome editing: recommendations, 12 July 2021 — global governance recommendations covering safety, ethics, registries, oversight, inequality, and international coordination.
  9. National Academy of Medicine, National Academy of Sciences, and Royal Society. Heritable Human Genome Editing, 2020 — scientific and translational criteria for any possible future clinical pathway.
  10. Nuffield Council on Bioethics. Genome editing and human reproduction: social and ethical issues, 2018 — welfare of the future person, social justice, public debate, safety, and regulatory conditions.
  11. Micera, Silvestro et al. Toward higher-performance bionic limbs for wider clinical use. Nature Biomedical Engineering, 2021 — neural interfaces, sensory feedback, osseointegration, embodiment and clinical translation of advanced prostheses.
  12. Nature Reviews Bioengineering. Prosthetic embodiment or what makes a limb part of your body, 2024 — overview of embodiment and sensory-functional integration in bionic prosthetics.
  13. Patrick-Krueger, K. Michelle, Ian Burkhart, and Jose L. Contreras-Vidal. The state of clinical trials of implantable brain–computer interfaces. Nature Reviews Bioengineering, 2025 — clinical landscape and translational limits of implanted BCIs.
  14. Reuters. China approves market launch of brain-computer interface medical device in world first, 13 March 2026 — current regulatory milestone for a minimally invasive therapeutic BCI aimed at quadriplegia.
  15. UNESCO. Recommendation on the Ethics of Neurotechnology, adopted by the 43rd General Conference in November 2025 — first global normative instrument focused on neurotechnology ethics.
  16. OECD. Recommendation / Responsible Innovation in Neurotechnology Enterprises, 2019 — privacy, enhancement, commercial manipulation, access inequalities, identity and responsible innovation concerns.
  17. Ploesser, Markus et al. Electrical and Magnetic Neuromodulation Technologies and Brain-Computer Interfaces: Ethical Considerations for Enhancement of Brain Function in Healthy People — A Systematic Scoping Review. 2024 — safety, efficacy, justice, identity and socioeconomic concerns.
  18. National Institute on Aging. Live Long in Good Health: Could Calorie Restriction Mimetics Hold the Key? — evidence boundary for calorie restriction and commercial anti-aging claims in humans.
  19. Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database. npj Aging, 2025 — methodological limitations and cross-species translation in preclinical anti-aging research.
  20. UNESCO. Universal Declaration on the Human Genome and Human Rights, 1997 — dignity, consent, non-discrimination, access to benefits of science and responsibilities in human-genome research.
  21. Chaproniere, Lysette. Is enhancement inherently ableist? Bioethics 36 (2022): 356–366 — analysis of enhancement, disability justice, genuine choice and accessible social environments.
  22. Loue, Sana; Harshita Kuna; Sean Eli McCormick. Difference or Defect? Disability Considered in the Context of Transhumanism. Journal of Intercultural Management and Ethics, 2025 — disability, enhancement access and ableism concerns.